Emerging research suggests a compelling link between the ketogenic diet and alterations in DNA methylation patterns. This remarkable dietary approach, characterized by high fat intake and restricted carbohydrate consumption, may profoundly influence gene expression by modifying the epigenome. While the precise mechanisms remain under investigation,
. this sort of experiments are identified as mutation accumulation (MA) experiments (Elena and Lenski 2003; Lind and Andersson 2008; Brockhurst et al. 2010). now it is possible to follow up MA experiments with full-genome sequencing in the ancestor strain and its resulting progeny, thus allowing to the genome-large identification of the MA mutation
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